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David Porciani
Fast-diffusing p75NTR monomers support apoptosis and growth cone collapse by neurotrophin ligands. Marchetti L, Bonsignore F, Gobbo F, Amodeo R, Calvello M, Jacob A, Signore G, Spagnolo CS, Porciani D, Mainardi M, Beltram F, Luin S, Cattaneo A. Proceedings of the National Academy of Sciences of the United States of America; 116(43):21563-21572.
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Peptide-Based Stealth Nanoparticles for Targeted and pH-Triggered Delivery. Ranalli A, Santi M, Capriotti L, Voliani V, Porciani D, Beltram F, Signore G. Bioconjugate Chemistry; 28(2):627-635.
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Aptamer-mediated codelivery of doxorubicin and NF-κB decoy enhances chemosensitivity of pancreatic tumor cells. Porciani D, Tedeschi L, Marchetti L, Citti L, Piazza V, Beltram F, Signore G. Molecular Therapy - Nucleic Acids; 4(4):e235.
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Two interconvertible folds modulate the activity of a DNA aptamer against transferrin receptor. Porciani D, Signore G, Marchetti L, Mereghetti P, Nifosì R, Beltram F. Molecular Therapy - Nucleic Acids; 3:e144.
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Aptamers with Tunable Affinity Enable Single-Molecule Tracking and Localization of Membrane Receptors on Living Cancer Cells. Delcanale P, Porciani D, Pujals S, Jurkevich A, Chetrusca A, Tawiah KD, Burke DH, Albertazzi L. Angewandte Chemie - International Edition; 59(42):18546-18555.
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Tumor-cell–macrophage fusion cells as liquid biomarkers and tumor enhancers in cancer. Manjunath Y, Porciani D, Mitchem JB, Suvilesh KN, Avella DM, Kimchi ET, Staveley-o’carroll KF, Burke DH, Li G, Kaifi JT. International Journal of Molecular Sciences; 21(5):1872.
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Therapeutic peptide delivery: Via aptamer-displaying, disulfide-linked peptide amphiphile micelles. Smith JD, Cardwell LN, Porciani D, Nolla A, Cornelison BT, Schulte MC, Gallazzi F, Burke DH, Daniels MA, Ulery BD. Molecular Systems Design and Engineering; 5(1):269-283.
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Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Porciani D, Cardwell LN, Tawiah KD, Alam KK, Lange MJ, Daniels MA, Burke DH. Nature Communications; 9(1):2283.
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Aptamer-displaying peptide amphiphile micelles as a cell-targeted delivery vehicle of peptide cargoes. Smith JD, Cardwell LN, Porciani D, Nguyen JA, Zhang R, Gallazzi F, Tata RR, Burke DH, Daniels MA, Ulery BD. Physical Biology; 15(6):065006.
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A Fluorescent Split Aptamer for Visualizing RNA-RNA Assembly in Vivo. Alam KK, Tawiah KD, Lichte MF, Porciani D, Burke DH. ACS Synthetic Biology; 6(9):1710-1721.
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Toward the selection of cell targeting aptamers with extended biological functionalities to facilitate endosomal escape of cargoes. Tawiah KD, Porciani D, Burke DH. Biomedicines; 5(3):51.
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