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Margaret Lange

Margaret Lange

Assistant Research Professor

Phone: 573-884-5159
LangeMj@missouri.edu
415 Bond Life Sciences Center

News about Margaret Lange

2020

Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase. Nguyen PDM, Zheng J, Gremminger TJ, Qiu L, Zhang D, Tuske S, Lange MJ, Griffin PR, Arnold E, Chen S-J, Zou X, Heng X, Burke DH. Nucleic Acids Research; 48(5):2709-2722.

Date published: March 18, 2020
Featured in this article: Margaret Lange, Donald Burke-Agüero.

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2019

Diphtheria Toxin A-Resistant Cell Lines Enable Robust Production and Evaluation of DTA-Encoding Lentiviruses. Lange MJ, Lyddon TD, Johnson MC. Scientific Reports; 9(1):8985.

Date published: December 1, 2019
Featured in this article: Margaret Lange, Terri Lyddon, Marc Johnson.

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GS-CA compounds: First-in-class HIV-1 capsid inhibitors covering multiple grounds. Singh K, Gallazzi F, Hill KJ, Burke DH, Lange MJ, Quinn TP, Neogi U, Sönnerborg A. Frontiers in Microbiology; 10(JUN):1227.

Date published: June 20, 2019
Featured in this article: Kamlendra Singh, Fabio Gallazzi, Donald Burke-Agüero, Margaret Lange, Thomas Quinn.

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Activation of Innate Immune Responses by a CpG Oligonucleotide Sequence Composed Entirely of Threose Nucleic Acid. Lange MJ, Burke DH, Chaput JC. Nucleic Acid Therapeutics; 29(1):51-59.

Date published: February 1, 2019
Featured in this article: Margaret Lange, Donald Burke-Agüero.

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2018

Poly-Target Selection Identifies Broad-Spectrum RNA Aptamers. Alam KK, Chang JL, Lange MJ, Nguyen PDM, Sawyer AW, Burke DH. Molecular Therapy - Nucleic Acids; 13:605-619.

Date published: December 7, 2018
Featured in this article: Margaret Lange, Donald Burke-Agüero.

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Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Porciani D, Cardwell LN, Tawiah KD, Alam KK, Lange MJ, Daniels MA, Burke DH. Nature Communications; 9(1):2283.

Date published: December 1, 2018
Featured in this article: David Porciani, Margaret Lange, Donald Burke-Agüero.

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2017

RNA-protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamers. Lange MJ, Nguyen PDM, Callaway MK, Johnson MC, Burke DH. Nucleic Acids Research; 45(10):6087-6097.

Date published: June 2, 2017
Featured in this article: Margaret Lange, Marc Johnson, Donald Burke-Agüero.

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2014

Screening inhibitory potential of anti-HIV RT RNA aptamers. Lange MJ, Burke DH. Methods in Molecular Biology; 1103:11-29.

Date published: January 1, 2014
Featured in this article: Margaret Lange, Donald Burke-Agüero.

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2013

Potent inhibition of HIV-1 reverse transcriptase and replication by nonpseudoknot, “UCAA-motif” RNA aptamers. Whatley AS, Ditzler MA, Lange MJ, Biondi E, Sawyer AW, Chang JL, Franken JD, Burke DH. Molecular Therapy - Nucleic Acids; 2:e71.

Date published: February 5, 2013
Featured in this article: Margaret Lange, Donald Burke-Agüero.

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High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase. Ditzler MA, Lange MJ, Bose D, Bottoms CA, Virkler KF, Sawyer AW, Whatley AS, Spollen W, Givan SA, Burke DH. Nucleic Acids Research; 41(3):1873-1884.

Date published: February 1, 2013
Featured in this article: Margaret Lange, Bill Spollen, Scott Givan, Donald Burke-Agüero.

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2012

Robust suppression of HIV replication by intracellularly expressed reverse transcriptase aptamers is independent of ribozyme processing. Lange MJ, Sharma TK, Whatley AS, Landon LA, Tempesta MA, Johnson MC, Burke DH. Molecular Therapy; 20(12):2304-2314.

Date published: December 1, 2012
Featured in this article: Margaret Lange, Marc Johnson, Donald Burke-Agüero.

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