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Margaret Lange

Margaret Lange

Assistant Research Professor

Phone: 573-884-5159
LangeMj@missouri.edu
415 Bond Life Sciences Center

News about Margaret Lange

Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase. Nguyen PDM, Zheng J, Gremminger TJ, Qiu L, Zhang D, Tuske S, Lange MJ, Griffin PR, Arnold E, Chen S-J, Zou X, Heng X, Burke DH. Nucleic Acids Research; 48(5):2709-2722.

Featured in this article: Margaret Lange, Donald Burke-Agüero.

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Diphtheria Toxin A-Resistant Cell Lines Enable Robust Production and Evaluation of DTA-Encoding Lentiviruses. Lange MJ, Lyddon TD, Johnson MC. Scientific Reports; 9(1):8985.

Featured in this article: Margaret Lange, Terri Lyddon, Marc Johnson.

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GS-CA compounds: First-in-class HIV-1 capsid inhibitors covering multiple grounds. Singh K, Gallazzi F, Hill KJ, Burke DH, Lange MJ, Quinn TP, Neogi U, Sönnerborg A. Frontiers in Microbiology; 10(JUN):1227.

Featured in this article: Kamlendra Singh, Fabio Gallazzi, Donald Burke-Agüero, Margaret Lange, Thomas Quinn.

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Activation of Innate Immune Responses by a CpG Oligonucleotide Sequence Composed Entirely of Threose Nucleic Acid. Lange MJ, Burke DH, Chaput JC. Nucleic Acid Therapeutics; 29(1):51-59.

Featured in this article: Margaret Lange, Donald Burke-Agüero.

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Poly-Target Selection Identifies Broad-Spectrum RNA Aptamers. Alam KK, Chang JL, Lange MJ, Nguyen PDM, Sawyer AW, Burke DH. Molecular Therapy - Nucleic Acids; 13:605-619.

Featured in this article: Margaret Lange, Donald Burke-Agüero.

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Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Porciani D, Cardwell LN, Tawiah KD, Alam KK, Lange MJ, Daniels MA, Burke DH. Nature Communications; 9(1):2283.

Featured in this article: David Porciani, Margaret Lange, Donald Burke-Agüero.

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RNA-protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamers. Lange MJ, Nguyen PDM, Callaway MK, Johnson MC, Burke DH. Nucleic Acids Research; 45(10):6087-6097.

Featured in this article: Margaret Lange, Marc Johnson, Donald Burke-Agüero.

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Screening inhibitory potential of anti-HIV RT RNA aptamers. Lange MJ, Burke DH. Methods in Molecular Biology; 1103:11-29.

Featured in this article: Margaret Lange, Donald Burke-Agüero.

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Potent inhibition of HIV-1 reverse transcriptase and replication by nonpseudoknot, “UCAA-motif” RNA aptamers. Whatley AS, Ditzler MA, Lange MJ, Biondi E, Sawyer AW, Chang JL, Franken JD, Burke DH. Molecular Therapy - Nucleic Acids; 2:e71.

Featured in this article: Margaret Lange, Donald Burke-Agüero.

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High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase. Ditzler MA, Lange MJ, Bose D, Bottoms CA, Virkler KF, Sawyer AW, Whatley AS, Spollen W, Givan SA, Burke DH. Nucleic Acids Research; 41(3):1873-1884.

Featured in this article: Margaret Lange, Christopher Bottoms, Bill Spollen , Scott Givan, Donald Burke-Agüero.

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Robust suppression of HIV replication by intracellularly expressed reverse transcriptase aptamers is independent of ribozyme processing. Lange MJ, Sharma TK, Whatley AS, Landon LA, Tempesta MA, Johnson MC, Burke DH. Molecular Therapy; 20(12):2304-2314.

Featured in this article: Margaret Lange, Marc Johnson, Donald Burke-Agüero.

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The importance of TLR3 expression and hormonal regulation of TLR3-induced immune responses in the human endometrium. Lange MJ, Misfeldt ML. Current Immunology Reviews; 5(3):215-226.

Featured in this article: Margaret Lange.

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Toll-like receptors in tonsillar epithelial cells. Lange MJ, Lasiter JC, Misfeldt ML. International Journal of Pediatric Otorhinolaryngology; 73(4):613-621.

Featured in this article: Margaret Lange.

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Toll-like receptor expression in the human nasopharyngeal tonsil (adenoid) and palantine tonsils: A preliminary report. Lesmeister MJ, Bothwell MR, Misfeldt ML. International Journal of Pediatric Otorhinolaryngology; 70(6):987-992.

Featured in this article: Margaret Lange.

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17beta-estradiol suppresses TLR3-induced cytokine and chemokine production in endometrial epithelial cells. Lesmeister MJ, Jorgenson RL, Young SL, Misfeldt ML. Reproductive Biology and Endocrinology; 3:74.

Featured in this article: Margaret Lange.

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Human endometrial epithelial cells cyclically express Toll-like receptor 3 (TLR3) and exhibit TLR3-dependent responses to dsRNA. Jorgenson RL, Young SL, Lesmeister MJ, Lyddon TD, Misfeldt ML. Human Immunology; 66(5):469-482.

Featured in this article: Margaret Lange, Terri Lyddon.

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