Archive
Trupti Joshi
Research Interests The Joshi lab has expertise in the areas of bioinformatics and its application to biomedical sciences, plants sciences, animal sciences, and health informatics fields. The lab has three key research pillars: Multiomics Informatics Data Analytics and Framework Development Multiomics Informatics Method Development Multiomics Data Integration Tool Development…
Chris and Monique Lorson
Research Interests The Lorson lab is comprised of several research teams largely centered on translational medicine and neurodegenerative diseases including Spinal Muscular Atrophy (SMA), SMA with Respiratory Distress (SMARD), Charcot-Marie-Tooth (CMT), and others. Current projects include: Development of a novel drug for SMA — a splice-switching antisense oligonucleotide — that dramatically extends survival in SMA animal models from a single dose at birth. Identification of genes and pathways that improve the SMA/SMARD phenotypes, such as Plastin-3 or alpha-synuclein and then validating these factors using AAV-mediated gene therapy. Small molecule development in collaboration with the Androphy lab (IUPUI) and the Hodgetts…