Research
April 13, 2022
Receptors Found to Help Patients with Sjögren’s Disease
The Baker lab poses for a group photograph. The lab has been working with specialized pro-resolving lipid mediators in efforts to help patients with Sjögren’s Disease. Photo by Karly Balslew, Bond LSC By Karly Balslew | Bond LSC Saliva is probably not the first thing that comes to mind when we think about eating our favorite foods. The clear liquid washes away food debris and bacteria, and it plays a vital role in maintaining our dental hygiene and oral health. You may take it for granted, but for patients with Sjögren’s disease, life without saliva is…
March 16, 2022
Competing with COVID: Researcher suggests varying from vaccines to fight virus
COVID-19 virus particles have spike proteins, represented in red, that attach to receptors on host cells. Antivirals block the receptors on host cells so the virus cannot infect more cells. | Creative Commons Photo By Cara Penquite | Bond LSC Vaccines were the light at the end of the tunnel throughout the COVID-19 pandemic, but virus mutations threaten to extinguish hope of a quick end to the pandemic. Kamlendra Singh turns towards antivirals as the next step. “There will be a time we will find an antiviral which will be very difficult for the virus to mutate…
March 3, 2022
Protecting Plants: Researchers identify genes responsible for vital antimicrobial proteins
DNA is the genetic material that determines the characteristics of plants and animals. Using CRISPR gene editing, researchers altered the characteristics of rice plants. | Creative Commons Photo by Pixabay By Cara Penquite | Bond LSC A tickle in the throat, a stuffy nose, congestion . . . the tell-tale signs of a cold are familiar to most, and many know that with enough rest, the immune cells on standby in the human body will destroy any invaders. But what happens when plants get sick? The Bing Yang Lab from the Bond Life Sciences Center at the…
Feb. 24, 2022
Another piece of the pathway: Stacey lab identifies enzyme key to regulating plant metabolism
Researcher Sung-Hwan Cho holds mutant Arabidopsis thalianas. The Gary Stacey lab used these mutant variations to study how plants react to external stressors. | Photo by Karly Balslew, Bond LSC By: Karly Balslew | Bond LSC When we get hurt, our body signals our brain to warn us about stress and damage. We acknowledge the damage and then initiate the proper steps to heal. Plants may have different receptors that read these stress signals, but the process is similar. “When someone crushes the plant tissue, this triggers their immune system like us,” said Sung-Hwan…
Feb. 17, 2022
Pancreatic tumor composition provides insight on treatment response
Jing Zhou focuses the microscope through her computer. The microscope feeds its view directly to her screen so Zhou can see the pancreatic cells. | Photo by Cara Penquite, Bond LSC By Cara Penquite | Bond LSC Not all tumors are created equal, and potential treatments aren’t universal. When it comes to pancreatic cancer, surgery and radiation often do more harm than good due to its rapid growth and ability to spread to the liver. Searching for alternative treatment options, Jing Zhou focused her research on immunotherapies. That led Zhou and her team to identify the sequences…
Feb. 9, 2022
Old Drugs, New Application: Artificial Intelligence Aid Future Breast Cancer Treatment
Photo by Christina Victoria Craft on Unsplash By Karly Balslew | Bond LSC New drug treatments take time and money to develop, especially with diseases as complicated as cancer. Developing a new drug to help cancer patients can take up to fifteen years and can cost roughly $1.6 billion, according to a paper published in the journal Cancers. With this in mind, researchers at the University of Missouri aim to capitalize on drugs that already exist. Using advanced computing, they are turning to FDA-approved drugs to repurpose, or reposition, for future cancer treatments. “The motivation…
Feb. 2, 2022
Outlining Omicron: researchers determine key mutations in the latest COVID-19 variant
Bond LSC and UNMC scientists explain mutations unique to the Omicron variant Austin Spratt, undergraduate mathematics student in the Kamlendra Singh lab, shows protein models of the Omicron spike protein and the receptor it attaches to when infecting cells. “The genetic codes are used to identify the mutations, and then we use the structure to see how it would change over time. It’s going to give us more information about new mutations that occur,” Spratt said. | Photo by Cara Penquite, Bond LSC By Cara Penquite | Bond LSC It took eight days for…
Dec. 20, 2021
New method leads to discovery of placental cell type
Nathan Bivens, director of the Genomics Technology Core at Bond Life Sciences Center, loads the Chromium 10X Genomics machine as part of the single-cell RNA sequence method. | photo by Lauren Hines, Bond LSC By Lauren Hines | Bond LSC During pregnancy, the fetus and mother can talk to each other without saying a word. On a deeper level, a special cell called the syncytiotrophoblast facilitates this conversation by changing the mother’s physiology based on what the fetus does or does not need. The Michael Roberts lab at Bond Life Sciences Center knew there had to…
Dec. 8, 2021
Bond LSC Researcher Wins Awards for 45-Year Career in Reproductive Biology
Even though Roberts couldn’t accept the award in person, the Chinese Association of Animal Science and Veterinary Medicine still held an award ceremony and presented the medal to one of Roberts’ past associates. | photo contributed by Michael Roberts, Bond LSC. By Lauren Hines | Bond LSC Still in the lab after 45 years, chancellor’s professor emeritus Michael Roberts has received recognition for his career in reproductive biology research. Roberts won the Marshall Medal from the UK Society for Reproduction and Fertility (SRF) in August and the Gold Medal and Honorable Membership of the Animal…
Nov. 10, 2021
Technique connects DNA instructions to biological architecture in space: Core collaboration maps the future
Nathan Bivens, director of the Genomics Technology Core at Bond Life Sciences Center, holds a special slide that assigns barcodes to expressed genes on different places on the tissue. This helps Bivens know where certain gene expressions came from on the tissue. | photo by Lauren Hines, Bond LSC By Lauren Hines | Bond LSC The brain is a unique challenge. It has billions of cells with billions of different functions, making it hard to understand what is going on underneath. MU cores now offer 10X Genomics Visium technology which allows researchers to lay genetic data…
Oct. 13, 2021
Turning Back the Clock
Megan Sheridan, a postdoctoral fellow working with the R. Michael Roberts lab, removes the base solution from a demonstrated sample of stem cells that will be grown into placental cells for study of their interaction with the Zika virus. | photo by Phillip Sitter, Bond LSC By Lauren Hines | Bond LSC At 24 weeks pregnant, a baby can hear the mother’s lullabies. At 30 weeks, her belly is a little over a foot large. At 40, the hospital bag is already packed and ready to go. But imagine delivering only two weeks…
Sep. 20, 2021
Finding a new direction to better corn nutrition
Arabidopsis plants line the shelves of a basement room in Bond LSC. The new biofortification direction the Angelovici lab found in maize seems to also be present in arabidopsis plants. | photo by Phillip Sitter, Bond LSC By Lauren Hines | Bond LSC Whether it’s through kernels, cereal or chips, corn pops up everywhere in our diet, providing nutrition to countless people all over the world. But that nourishment isn’t enough to be satisfied, especially when a staple so widespread still lacks some building blocks key to balanced nutrition. Researchers have tried different reverse genetics approaches…