science // Bond Life Sciences Center

June 26, 2015

The view from the trenches: a conversation about Alzheimer’s disease

This immunofluorescence picture shows the brain of an Alzheimer’s disease mouse model, also known as the TgCRND8 mouse. In the picture, the amyloid beta plaques are stained green and the microglia, or immune cells of the brain, are stained red. Image courtesy of Luke Woods. By Caleb O’Brien | MU Bond Life Sciences Center Jean Camden…

March 12, 2015

Five things you wanted to know about epigenetics (But were afraid to ask)

What the heck is it, anyway? Epigenetics involves changes in how your genes work. In classical genetics, traits pass from generation to generation in DNA, the strands of genetic material that encode your genes. Scientists thought alterations to the DNA itself was the only way changes could pass on to subsequent generations. So say you…

Aug. 4, 2014

Viruses as Vehicles: Finding what drives

Graduate students Yuleam Song and Dan Salamango inoculate a bacteria culture in Johnson’s lab. The inoculation takes a small portion of a virus and multiplies the sample, allowing researchers to custom-make viruses. By Madison Knapp | Bond Life Sciences Center summer intern Modern science has found a way to turn viruses —tiny, dangerous weapons responsible…

July 16, 2014

Researchers flex new muscle in SMA drug development

By Paige Blankenbuehler Lauren and Claire Gibbs share contagious laughter, ambition and a charismatic sarcasm. Both are honor students at Shawnee Mission East High School in a Kansas City suburb. They also share a neuromuscular disease called spinal muscular atrophy (SMA), designated as an “orphan disease” because it affects fewer than 200,000 people in the…

June 20, 2014

Nerve cell communication mechanisms uncovered, may lead to new therapeutic approaches for neurodegenerative diseases

Story by Madison Knapp/ Bond Life Sciences summer intern Simple actions like walking, swallowing and breathing are the result of a complex communication system between cells. When we touch something hot, our nerve cells tell us to take our hand off the object. This happens in a matter of milliseconds. This hyperspeed of communication…

June 10, 2014

SoyKB: Leading the convergence of wet and dry science in the era of Big Data

Yaya Cui, an investigator in plant sciences at the Bond Life Sciences Center examines data on fast neuron soybean mutants that are represented on the SoyKB database. The most puzzling scientific mysteries may be solved at the same machine you’re likely reading this sentence. In the era of “Big Data” many significant scientific discoveries —…

April 25, 2014

Frogs help researchers find genetic mechanism for mildew susceptibility in grapevine

Powdery mildew on a cabernet sauvignon grapevine leaf. | USDA Grape genetics publications and research A princess kisses a frog and it turns into a prince, but when a scientist uses a frog to find out more information about a grapevine disease, it turns into the perfect tool narrowing in on the cause of crop…

March 21, 2014

MU researchers find key gene in spinal locomotion, yield insight on paralysis

Samuel Waters and graduate researcher Desiré Buckley review stages of embryonic development. — BLANKENBUEHLER The difference between walking and being paralyzed could be as simple as turning a light switch on and off, a culmination of years of research shows. Recently, University of Missouri Assistant Professor of biology Samuel T. Waters isolated a coding gene…

Feb. 7, 2014

Quicker anthrax detection could save millions of dollars, speed bioterror response

Anthrax bacteria is a rod-shaped culture. Most common forms of transmission are through abrasions in the skin and inhalation. Imagine researchers in hazmat suits moving slowly and deliberately through a lab. One of them holds up a beaker. It’s glowing. This light — or the absence of it — could save millions of dollars…