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SMA

Nov. 17, 2016

Live long and prosper: healthy mitochondria, healthy motor neurons?

Live long and prosper: healthy mitochondria, healthy motor neurons?

Chris Lorson (front) and Mark Hannink (back) collaborate to study the role of mitochondria in motor neuron health, particularly in relation to spinal muscular atrophy, a neuromuscular disorder | photo by Jen Lu, Bond LSC Chris Lorson, a professor of veterinary pathobiology, and Mark Hannink, a professor of biochemistry, want to find a new way…

July 21, 2016

Finding hope by fixing a gene

Finding hope by fixing a gene

Lorson lab publishes research on a new therapeutic path to help treat spinal muscular atrophy By Phillip Sitter | MU Bond Life Sciences Center Erkan Osman shows iImages of neuro-muscular junctions. Osman, a post-doctoral fellow in Chris Lorson’s lab, co-authored research in the journal Molecular Therapy that details work in binding a synthetic nucleic acid…

July 16, 2014

Researchers flex new muscle in SMA drug development

Researchers flex new muscle in SMA drug development

By Paige Blankenbuehler Lauren and Claire Gibbs share contagious laughter, ambition and a charismatic sarcasm. Both are honor students at Shawnee Mission East High School in a Kansas City suburb. They also share a neuromuscular disease called spinal muscular atrophy (SMA), designated as an “orphan disease” because it affects fewer than 200,000 people in the…