viruses
April 30, 2020
Treating COVID-19: Bond LSC lab explores effectiveness of remdesivir and other potential drugs
By Jerry Duggan | Bond LSC As countries hang their hopes on the drug remdesivir for battling COVID-19, recent modeling and computer-aided drug evaluation at the University of Missouri caution to keep an open mind to other drug treatments. Kamlendra Singh at MU’s Bond Life Sciences Center assessed remdesivir and several other drugs for long-term success in treating coronavirus causing the pandemic across the world. His results were published April 26 in the journal Pathogens. “Remdesivir is working against COVID-19, but these other drugs are in no way inferior to it,”…
Aug. 26, 2014
Holding on: Bond LSC scientist discovers protein prevents release of HIV and other viruses from infected cells
Shan-Lu Liu, Bond LSC scientist and associate professor in the MU School of Medicine’s Department of Molecular Microbiology and Immunology. Courtesy Justin Kelley, University of Missouri Health System. Shan-Lu Liu initially thought it was a mistake when a simple experiment kept failing. But that serendipitous accident led the Bond Life Sciences Center researcher to discover how a protein prevents mature HIV from leaving a cell. Proceedings of the National Academy of Sciences published this research online Aug. 18. “It’s a striking phenomena caused by this particular protein,” Liu said. “The HIV is already assembled inside…
Aug. 4, 2014
Viruses as Vehicles: Finding what drives
Graduate students Yuleam Song and Dan Salamango inoculate a bacteria culture in Johnson’s lab. The inoculation takes a small portion of a virus and multiplies the sample, allowing researchers to custom-make viruses. By Madison Knapp | Bond Life Sciences Center summer intern Modern science has found a way to turn viruses —tiny, dangerous weapons responsible for runny noses, crippling stomach pains and worldwide epidemics such as AIDS— into a tool. Gene therapy centers on the idea that scientists can hijack viruses and use them as vehicles to deliver DNA to organs in the body that…