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A simple virtue lies at the heart of Xuemin (Sam) Wang’s research: thrift. “A good way to think of it is how to increase output without demanding more inputs,” Wang said. Wang, the E. Desmond Lee and Family Fund endowed professor at the University of Missouri-St. Louis and a principal investigator at the Donald Danforth…
Joya Chandra, associate professor of pediatrics at The University of Texas MD Anderson Cancer Center, explains the epigenetics of pediatric cancers at the 2015 MU LSSP Symposium on epigenetics on Sunday, March 15.//photo by Caleb O’Brien/Bond LSC The evolving science of epigenetics is shaking up how scientists and doctors think about cancer. At the 11th…
Roger Meissen/Bond Life Sciences Center – These soybean roots show some nematode cysts. The small, white circles are the hardened body of the nematodes and form when the nematode attaches itself to the root to create a feeding cell. Beneath a North Carolina field in 1954, a tiny worm inched its way through the soil…
What the heck is it, anyway? Epigenetics involves changes in how your genes work. In classical genetics, traits pass from generation to generation in DNA, the strands of genetic material that encode your genes. Scientists thought alterations to the DNA itself was the only way changes could pass on to subsequent generations. So say you…
LSSP Symposium highlights epigenetics of the womb and how parental stress can change genetic makeup Could a stressful day during pregnancy change the future of a developing child nestled in the womb? Experts in the epigenetic research field are saying yes. This weekend the 11th annual Life Sciences and Society Program will kick off “Epigenetic…
To introduce our 11th Annual Life Sciences and Society Program, The Epigenetics Revolution: Nature, Nurture and What Lies Ahead that runs at the University of Missouri March 13-15, we figured it would be nice to define the term epigenetics. Spoiler: It’s amazing and it could change everything. According to Merriam-Webster Dictionary, epigenetics is “the study of heritable changes…
Bond LSC’s Jack Schultz and Heidi Appel hold model Arabidopsis plants used in many of their experiments. Roger Meissen/Bond LSC We often think of damage on a surface level. But for plants, much of the important response to an insect bite takes place out of sight. Over minutes and hours, particular plant genes are turned…
Adeno-associated virus type 2 at 3.0 A (xie, et al, Proc Natl Acad Sci U S A. 2002; 99:10405-10.) Courtesy David Pintel It’s an understatement to say viruses are small. But an average virus dwarfs the diminutive variety known as parvoviruses, which are among the most minuscule pathogens known to science. Tucked inside a protective…
Protein specimens are prepared here in a Bond Life Sciences lab. Bond LSC’s Mark Hannink recently identified a protein pathway could be useful in restoring mitochondrial recycling in certain cells, a problem that leads to familial Parkinson’s Disease. It’s as if your recycling man quit his job and never came back. Bags pile up to unexpected…
A mutant arabidopsis model nearing pollination. Mutant arabidopsis models under lamps in Shuqun Zhang's lab. Three-month-old mutant arabidopsis models are used to study the function of pollen. The thought of pollen dispersed throughout the air might trigger horrific memories of allergies, but the drifting dander is absolutely essential to all life. Science has long linked…
