People
Donald Burke-Agüero
Professor, Molecular Microbiology and Immunology & Biochemistry
Phone: 573-884-1316
burkedh@missouri.edu
471H Bond Life Sciences Center
Donald Burke-Agüero is a professor of molecular microbiology and immunology and joint professor of biochemistry.
Burke explores the many roles of ribonucleic acid, or RNA. This substance has long been known to function in cells to help copy genetic information from DNA. But scientists are increasingly recognizing many other tasks that RNA carries out. Burke uses cell biology, biochemistry, and sophisticated computational approaches to compare millions of RNA molecules, looking for the ones that can do helpful jobs. He foresees that RNA might be harnessed for artificial metabolisms or to direct the development of stem cells. Burke has developed RNA molecules called aptamers that bind tightly to proteins from HIV and prevent this virus from replicating. His lab also uses molecular evolution techniques to develop artificial ribozymes, which are RNA molecules that catalyze chemical reactions. These have implications for the study of evolution because the earliest life on Earth is widely thought to have evolved through RNA.
Lab site: Burke Lab
News about Donald Burke-Agüero
Research Topics
- Artificial RNA
- Directed Molecular Evolution
- Evolution
- Gene Therapy
- Molecular
- Nucleic Acid
- Replication
- Ribozyme
- RNA
- Virus
2023
Minimizing amplification bias during reverse transcription for in vitro selections. Lucas, Jordyn K.; Gruenke, Paige R.; Burke, Donald H.. RNA; Volume 29, Issue 8, Pages 1301 - 1316.
Date published: August 1, 2023Featured in this article: Donald Burke-Agüero.
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Valency and affinity control of aptamer-conjugated nanoparticles for selective cancer cell targeting. Woythe, Laura; Porciani, David; Harzing, Tessa; van Veen, Stijn; Burke, Donald H.; Albertazzi, Lorenzo. Journal of Controlled Release; Volume 355, Pages 228 - 237.
Date published: March 1, 2023Featured in this article: Donald Burke-Agüero.
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2022
An RNA aptamer that shifts the reduction potential of metabolic cofactors. Samuelian J S, Gremminger T J, Song Z, Poudyal R R, Li J, Zhou Y, Staller S A, Carballo J A, Roychowdhury-Saha M, Chen S, Burke D H, Heng X. Nature Chemical Biology; Volume 18, Issue 11, Pages 1263 - 1269.
Date published: November 1, 2022Featured in this article: Donald Burke-Agüero.
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FASTAptameR 2.0: A web tool for combinatorial sequence selections. Kramer S T, Gruenke P R, Alam K K, Xu D, Burke D H. Molecular Therapy - Nucleic Acids; Volume 29, Pages 862 - 870.
Date published: September 13, 2022Featured in this article: Skyler Kramer, Dong Xu, Donald Burke-Agüero.
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Aptamers Targeting Hallmark Proteins of Neurodegeneration. Mollasalehi, Niloufar, Francois-Moutal, Liberty, Porciani, David,Burke, Donald H., Khanna, May. Nucleic Acid Therapeutics; Volume 32, Issue 4, Pages 235 - 250.
Date published: August 1, 2022Featured in this article: Donald Burke-Agüero, .
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A label free, signal off electrochemical aptasensor for amphetamine detection. Shoni, Shringika ; Jain, Utkarsh; Bruke, Donald H. , Chauhan, Nidhi. Surfaces and Interfaces; Article number 102023.
Date published: July 1, 2022Featured in this article: Donald Burke-Agüero.
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Development of Nanomaterial-Modified Impedimetric Aptasensor—A Single-Step Strategy for 3,4-Methylenedioxymethylamphetamine Detection. Soni, Shringika, Jain, Utkarsh, Burke, Donald H, Chauhan, Nidhi. Biosensors; Volume 12, Issue 7.
Date published: July 1, 2022Featured in this article: Donald Burke-Agüero.
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Recent trends and emerging strategies for aptasensing technologies for illicit drugs detection. Soni S., Jain U., Burke D.H. , Chauhan N.. Journal of Electroanalytical Chemistry; Volume 910.
Date published: April 1, 2022Featured in this article: Donald Burke-Agüero.
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Cancer immunomodulation using bispecific aptamers. Thomas B.J. , Porciani D. , Burke D.H.. Molecular Therapy - Nucleic Acids; Volume 27, Pages 894 - 915.
Date published: March 8, 2022Featured in this article: Donald Burke-Agüero, Brian Thomas, .
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Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication. Gruenke P.R. , Aneja R. , Welbourn S. , Ukah O.B. , Sarafianos S.G. , Burke D.H. , Lange M.J.. Nucleic Acids Research; Volume 50, Issue 3, Pages 1701 - 1717.
Date published: February 22, 2022Featured in this article: Donald Burke-Agüero.
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2020
2′-fluoro-modified pyrimidines enhance affinity of RNA oligonucleotides to HIV-1 reverse transcriptase. Gruenke, PR, Alam, KK, Singh K, Burke DH. RNA; 26(11):1667-1679.
Date published: November 1, 2020Featured in this article: Kamlendra Singh, Donald Burke-Agüero.
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Aptamers with Tunable Affinity Enable Single-Molecule Tracking and Localization of Membrane Receptors on Living Cancer Cells. Delcanale P, Porciani D, Pujals S, Jurkevich A, Chetrusca A, Tawiah KD, Burke DH, Albertazzi L. Angewandte Chemie - International Edition; 59(42):18546-18555.
Date published: October 12, 2020Featured in this article: Donald Burke-Agüero.
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Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase. Nguyen PDM, Zheng J, Gremminger TJ, Qiu L, Zhang D, Tuske S, Lange MJ, Griffin PR, Arnold E, Chen S-J, Zou X, Heng X, Burke DH. Nucleic Acids Research; 48(5):2709-2722.
Date published: March 18, 2020Featured in this article: Donald Burke-Agüero.
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Tumor-cell–macrophage fusion cells as liquid biomarkers and tumor enhancers in cancer. Manjunath Y, Porciani D, Mitchem JB, Suvilesh KN, Avella DM, Kimchi ET, Staveley-o’carroll KF, Burke DH, Li G, Kaifi JT. International Journal of Molecular Sciences; 21(5):1872.
Date published: March 1, 2020Featured in this article: Donald Burke-Agüero.
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Therapeutic peptide delivery: Via aptamer-displaying, disulfide-linked peptide amphiphile micelles. Smith JD, Cardwell LN, Porciani D, Nolla A, Cornelison BT, Schulte MC, Gallazzi F, Burke DH, Daniels MA, Ulery BD. Molecular Systems Design and Engineering; 5(1):269-283.
Date published: January 1, 2020Featured in this article: Donald Burke-Agüero.
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2019
GS-CA compounds: First-in-class HIV-1 capsid inhibitors covering multiple grounds. Singh K, Gallazzi F, Hill KJ, Burke DH, Lange MJ, Quinn TP, Neogi U, Sönnerborg A. Frontiers in Microbiology; 10(JUN):1227.
Date published: June 20, 2019Featured in this article: Kamlendra Singh, Donald Burke-Agüero.
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Strain-specific effect on biphasic DNA binding by HIV-1 integrase. Hill KJ, Rogers LC, Njenda DT, Burke DH, Sarafianos SG, Sonnerborg A, Neogi U, Singh K. AIDS; 33(3):588-592.
Date published: March 1, 2019Featured in this article: Donald Burke-Agüero, Kamlendra Singh.
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Activation of Innate Immune Responses by a CpG Oligonucleotide Sequence Composed Entirely of Threose Nucleic Acid. Lange MJ, Burke DH, Chaput JC. Nucleic Acid Therapeutics; 29(1):51-59.
Date published: February 1, 2019Featured in this article: Donald Burke-Agüero.
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2018
Poly-Target Selection Identifies Broad-Spectrum RNA Aptamers. Alam KK, Chang JL, Lange MJ, Nguyen PDM, Sawyer AW, Burke DH. Molecular Therapy - Nucleic Acids; 13:605-619.
Date published: December 7, 2018Featured in this article: Donald Burke-Agüero.
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Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines. Porciani D, Cardwell LN, Tawiah KD, Alam KK, Lange MJ, Daniels MA, Burke DH. Nature Communications; 9(1):2283.
Date published: December 1, 2018Featured in this article: Donald Burke-Agüero.
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Aptamer-displaying peptide amphiphile micelles as a cell-targeted delivery vehicle of peptide cargoes. Smith JD, Cardwell LN, Porciani D, Nguyen JA, Zhang R, Gallazzi F, Tata RR, Burke DH, Daniels MA, Ulery BD. Physical Biology; 15(6):065006.
Date published: October 22, 2018Featured in this article: Donald Burke-Agüero.
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2017
A Fluorescent Split Aptamer for Visualizing RNA-RNA Assembly in Vivo. Alam KK, Tawiah KD, Lichte MF, Porciani D, Burke DH. ACS Synthetic Biology; 6(9):1710-1721.
Date published: September 15, 2017Featured in this article: Donald Burke-Agüero.
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Toward the selection of cell targeting aptamers with extended biological functionalities to facilitate endosomal escape of cargoes. Tawiah KD, Porciani D, Burke DH. Biomedicines; 5(3):51.
Date published: September 1, 2017Featured in this article: Donald Burke-Agüero.
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RNA-protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamers. Lange MJ, Nguyen PDM, Callaway MK, Johnson MC, Burke DH. Nucleic Acids Research; 45(10):6087-6097.
Date published: June 2, 2017Featured in this article: Marc Johnson, Donald Burke-Agüero.
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Selective Inactivation of Functional RNAs by Ribozyme-Catalyzed Covalent Modification. Poudyal RR, Benslimane M, Lokugamage MP, Callaway MK, Staller S, Burke DH. ACS Synthetic Biology; 6(3):528-534.
Date published: March 17, 2017Featured in this article: Donald Burke-Agüero.
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Nucleobase modification by an RNA enzyme. Poudyal RR, Nguyen PDM, Lokugamage MP, Callaway MK, Gavette JV, Krishnamurthy R, Burke DH. Nucleic Acids Research; 45(3):1345-1354.
Date published: February 17, 2017Featured in this article: Donald Burke-Agüero.
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2016
Preparation of ribosomes for smFRET studies: A simplified approach. Shebl B, Menke DE, Pennella M, Poudyal RR, Burke DH, Cornish PV. Archives of Biochemistry and Biophysics; 603:118-130.
Date published: August 1, 2016Featured in this article: Donald Burke-Agüero.
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In vivo analysis of infectivity, fusogenicity, and incorporation of a mutagenic viral glycoprotein library reveals determinants for virus incorporation. Salamango DJ, Alam KK, Burke DH, Johnson MC. Journal of Virology; 90(14):6502-6514.
Date published: May 4, 2016Featured in this article: Donald Burke-Agüero, Marc Johnson.
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2015
FASTAptamer: A bioinformatic toolkit for high-throughput sequence analysis of combinatorial selections. Alam KK, Chang JL, Burke DH. Molecular Therapy - Nucleic Acids; 4(3):e230.
Date published: March 1, 2015Featured in this article: Donald Burke-Agüero.
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Preface. Chen S-J, Burke-Agüero DH. Methods in Enzymology; 553:xv-xvii.
Date published: January 1, 2015Featured in this article: Donald Burke-Agüero.
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Preface. Burke-Aguero DH. Methods in Enzymology; 550:xv-xix.
Date published: January 1, 2015Featured in this article: Donald Burke-Agüero.
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2014
Screening inhibitory potential of anti-HIV RT RNA aptamers. Lange MJ, Burke DH. Methods in Molecular Biology; 1103:11-29.
Date published: January 1, 2014Featured in this article: Donald Burke-Agüero.
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RNA structural analysis by enzymatic digestion. Biondi E, Burke DH. Methods in Molecular Biology; 1086:41-52.
Date published: January 1, 2014Featured in this article: Donald Burke-Agüero.
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Preface. Burke-Aguero DH. Methods in Enzymology; 549(C):xix-xxiii.
Date published: January 1, 2014Featured in this article: Donald Burke-Agüero.
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2013
Lewis acid catalysis of phosphoryl transfer from a copper(II)-NTP complex in a kinase ribozyme. Biondi E, Poudyal RR, Forgy JC, Sawyer AW, Maxwell AWR, Burke DH. Nucleic Acids Research; 41(5):3327-3328.
Date published: March 1, 2013Featured in this article: Donald Burke-Agüero.
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Potent inhibition of HIV-1 reverse transcriptase and replication by nonpseudoknot, “UCAA-motif” RNA aptamers. Whatley AS, Ditzler MA, Lange MJ, Biondi E, Sawyer AW, Chang JL, Franken JD, Burke DH. Molecular Therapy - Nucleic Acids; 2:e71.
Date published: February 5, 2013Featured in this article: Donald Burke-Agüero.
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High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase. Ditzler MA, Lange MJ, Bose D, Bottoms CA, Virkler KF, Sawyer AW, Whatley AS, Spollen W, Givan SA, Burke DH. Nucleic Acids Research; 41(3):1873-1884.
Date published: February 1, 2013Featured in this article: Donald Burke-Agüero.
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2012
Robust suppression of HIV replication by intracellularly expressed reverse transcriptase aptamers is independent of ribozyme processing. Lange MJ, Sharma TK, Whatley AS, Landon LA, Tempesta MA, Johnson MC, Burke DH. Molecular Therapy; 20(12):2304-2314.
Date published: December 1, 2012Featured in this article: Marc Johnson, Donald Burke-Agüero.
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A small ribozyme with dual-site kinase activity. Biondi E, Maxwell AWR, Burke DH. Nucleic Acids Research; 40(15):7528-7540.
Date published: August 1, 2012Featured in this article: Donald Burke-Agüero.
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Separating and analyzing sulfur-containing rnas with organomercury gels. Biondi E, Burke DH. Methods in Molecular Biology; 883:111-120.
Date published: April 6, 2012Featured in this article: Donald Burke-Agüero.
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Cell-penetrating RNAs: New keys to the castle. Burke DH. Molecular Therapy; 20(2):251-253.
Date published: February 1, 2012Featured in this article: Donald Burke-Agüero.
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Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase. Ndongwe TP, Adedeji AO, Michailidis E, Ong YT, Hachiya A, Marchand B, Ryan EM, Rai DK, Kirby KA, Whatley AS, Burke DH, Johnson M, Ding S, Zheng Y-M, Liu S-L, Kodama E-I, Delviks-Frankenberry KA, Pathak VK, Mitsuya H, Parniak MA, Singh K, Sarafianos SG. Nucleic Acids Research; 40(1):345-359.
Date published: January 1, 2012Featured in this article: Donald Burke-Agüero, Marc Johnson, Kamlendra Singh.
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2011
Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates. Ditzler MA, Bose D, Shkriabai N, Marchand B, Sarafianos SG, Kvaratskhelia M, Burke DH. Nucleic Acids Research; 39(18):8237-8247.
Date published: October 1, 2011Featured in this article: Donald Burke-Agüero.
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Conformational heterogeneity and the determinants of tertiary stabilization in the hammerhead ribozyme from Dolichopoda cave crickets. Roychowdhury-Saha M, Roychowdhury S, Burke DH. RNA Biology; 8(5).
Date published: September 1, 2011Featured in this article: Donald Burke-Agüero.
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2010
Assembly and activation of a kinase ribozyme. Burke DH, Rhee SS. RNA; 16(12):2349-2359.
Date published: December 1, 2010Featured in this article: Donald Burke-Agüero.
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Convergent donor and acceptor substrate utilization among kinase ribozymes. Biondi E, Nickens DG, Warren S, Saran D, Burke DH. Nucleic Acids Research; 38(19):6785-6795.
Date published: October 1, 2010Featured in this article: Donald Burke-Agüero.
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Template-directed ligation of tethered mononucleotides by T4 DNA ligase for kinase ribozyme selection. Nickens DG, Bardiya N, Patterson JT, Burke DH. PLoS ONE; 5(8):e12368.
Date published: August 24, 2010Featured in this article: Donald Burke-Agüero.
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2008
Novel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases. Michalowski D, Chitima-Matsiga R, Held DM, Burke DH. Nucleic Acids Research; 36(22):7124-7135.
Date published: December 1, 2008Featured in this article: Donald Burke-Agüero.
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2007
Active site binding and sequence requirements for inhibition of HIV-1 reverse transcriptase by the RT1 family of single-stranded DNA aptamers. Kissel JD, Held DM, Hardy RW, Burke DH. Nucleic Acids Research; 35(15):5039-5050.
Date published: August 1, 2007Featured in this article: Donald Burke-Agüero.
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Distinct reaction pathway promoted by non-divalent-metal cations in a tertiary stabilized hammerhead ribozyme. Roychowdhury-Saha M, Burke DH. RNA; 13(6):841-848.
Date published: June 1, 2007Featured in this article: Donald Burke-Agüero.
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Cross-clade inhibition of recombinant human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus SIVcpz reverse transcriptases by RNA pseudoknot aptamers. Held DM, Kissel JD, Thacker SJ, Michalowski D, Saran D, Ji A, Hardy RW, Rossi JJ, Burke DH. Journal of Virology; 81(10):5375-5384.
Date published: May 1, 2007Featured in this article: Donald Burke-Agüero.
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Single-stranded DNA aptamer RT1t49 inhibits RT polymerase and RNase H functions of HIV type 1, HIV type 2, and SIVCPZ RTs. Kissel JD, Held DM, Hardy RW, Burke DH. AIDS Research and Human Retroviruses; 23(5):699-708.
Date published: May 1, 2007Featured in this article: Donald Burke-Agüero.
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Conformational dynamics of self-thiophosphorylating RNA. Cho B-R, Burke DH. Bulletin of the Korean Chemical Society; 28(3):463-466.
Date published: March 1, 2007Featured in this article: Donald Burke-Agüero.
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A versatile photocleavable bifunctional linker for facile synthesis of substrate-DNA conjugates for the selection of nucleic acid catalysts. Saran D, Burke DH. Bioconjugate Chemistry; 18(1):275-279.
Date published: January 1, 2007Featured in this article: Donald Burke-Agüero.
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2006
Topological rearrangement yields structural stabilization and interhelical distance constraints in the Kin.46 self-phosphorylating ribozyme. Cho B, Burke DH. RNA; 12(12):2118-2125.
Date published: December 1, 2006Featured in this article: Donald Burke-Agüero.
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HIV-1 reverse transcriptase pausing at bulky 2′ adducts is relieved by deletion of the RNase H domain. Patterson JT, Nickens DG, Burke DH. RNA Biology; 3(4):163-169.
Date published: October 1, 2006Featured in this article: Donald Burke-Agüero.
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Differential susceptibility of HIV-1 reverse transcriptase to inhibition by RNA aptamers in enzymatic reactions monitoring specific steps during genome replication. Held DM, Kissel JD, Saran D, Michalowski D, Burke DH. Journal of Biological Chemistry; 281(35):25712-25722.
Date published: September 1, 2006Featured in this article: Donald Burke-Agüero.
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Extraordinary rates of transition metal ion-mediated ribozyme catalysis. Roychowdhury-Saha M, Burke DH. RNA; 12(10):1846-1852.
Date published: August 15, 2006Featured in this article: Donald Burke-Agüero.
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Multiple-turnover thio-ATP hydrolase and phospho-enzyme intermediate formation activities catalyzed by an RNA enzyme. Saran D, Held DM, Burke DH. Nucleic Acids Research; 34(11):3201-3208.
Date published: June 1, 2006Featured in this article: Donald Burke-Agüero.
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HIV-1 inactivation by nucleic acid aptamers. Held DM, Kissel JD, Patterson JT, Nickens DG, Burke DH. Frontiers in Bioscience; 11(1 P.1-446):89-112.
Date published: January 1, 2006Featured in this article: Donald Burke-Agüero.
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2005
A trans acting ribozyme that phosphorylates exogenous RNA. Saran D, Nickens DG, Burke DH. Biochemistry; 44(45):15007-15016.
Date published: November 15, 2005Featured in this article: Donald Burke-Agüero.
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Low-magnesium, trans-cleavage activity by type III, tertiary stabilized hammerhead ribozymes with stem 1 discontinuities. Burke DH, Travis Greathouse S. BMC Biochemistry; 6:14.
Date published: August 12, 2005Featured in this article: Donald Burke-Agüero.
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2004
Artificial tertiary motifs stabilize trans-cleaving hammerhead ribozymes under conditions of submillimolar divalent ions and high temperatures. Saksmerprome V, Roychowdhury-Saha M, Jayasena S, Khvorova A, Burke DH. RNA; 10(12):1916-1924.
Date published: December 1, 2004Featured in this article: Donald Burke-Agüero.
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Deprotonation stimulates productive folding in allosteric TRAP hammerhead ribozymes. Saksmerprome V, Burke DH. Journal of Molecular Biology; 341(3):685-694.
Date published: August 13, 2004Featured in this article: Donald Burke-Agüero.
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Tris(2-carboxyethyl)phosphine stabilization of RNA: Comparison with dithiothreitol for use with nucleic acid and thiophosphoryl chemistry. Rhee SS, Burke DH. Analytical Biochemistry; 325(1):137-143.
Date published: February 1, 2004Featured in this article: Donald Burke-Agüero.
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2003
The tyranny of adenosine recognition among RNA aptamers to coenzyme A. Saran D, Frank J, Burke DH. BMC Evolutionary Biology; 3:26.
Date published: December 19, 2003Featured in this article: Donald Burke-Agüero.
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Structural Flexibility and the Thermodynamics of Helix Exchange Constrain Attenuation and Allosteric Activation of Hammerhead Ribozyme TRAPs. Saksmerprome V, Burke DH. Biochemistry; 42(47):13879-13886.
Date published: December 2, 2003Featured in this article: Donald Burke-Agüero.
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Nickel2+-mediated assembly of an RNA-amino acid complex. Hati S, Boles AR, Zaborske JM, Bergman B, Posto AL, Burke DH. Chemistry and Biology; 10(11):1129-1137.
Date published: November 1, 2003Featured in this article: Donald Burke-Agüero.
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Evolutionary landscapes for the acquisition of new ligand recognition by RNA aptamers. Held DM, Greathouse ST, Agrawal A, Burke DH. Journal of Molecular Evolution; 57(3):299-308.
Date published: September 1, 2003Featured in this article: Donald Burke-Agüero.
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Inhibition of HIV-1 reverse transcriptase by RNA aptamers in Escherichia coli. Nickens DG, Patterson JT, Burke DH. RNA; 9(9):1029-1033.
Date published: September 1, 2003Featured in this article: Donald Burke-Agüero.
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2002
Expressing RNA aptamers inside cells to reveal proteome and ribonome function. Burke DH, Nickens DG. Briefings in Functional Genomics and Proteomics; 1(2):169-188.
Date published: July 1, 2002Featured in this article: Donald Burke-Agüero.
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Allosteric hammerhead ribozyme TRAPs. Burke DH, Ozerova NDS, Nilsen-Hamilton M. Biochemistry; 41(21):6588-6594.
Date published: May 28, 2002Featured in this article: Donald Burke-Agüero.
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Boron-containing aptamers to ATP. Lato SM, Ozerova NDS, He K, Sergueeva Z, Shaw BR, Burke DH. Nucleic Acids Research; 30(6):1401-1407.
Date published: March 15, 2002Featured in this article: Donald Burke-Agüero.
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Flavin recognition by an RNA aptamer targeted toward FAD. Roychowdhury-Saha M, Lato SM, Shank ED, Burke DH. Biochemistry; 41(8):2492-2499.
Date published: February 26, 2002Featured in this article: Donald Burke-Agüero.
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1998
Recombination, RNA evolution, and bifunctional RNA molecules isolated through chimeric SELEX. Burke DH, Willis JH. RNA; 4(9):1165-1175.
Date published: September 1, 1998Featured in this article: Donald Burke-Agüero.
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A novel acidophilic RNA motif that recognizes coenzyme A. Burke DH, Hoffman DC. Biochemistry; 37(13):4653-4663.
Date published: March 31, 1998Featured in this article: Donald Burke-Agüero.
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1997
RNA aptamers to the peptidyl transferase inhibitor chloramphenicol. Burke DH, Hoffman DC, Brown A, Hansen M, Pardi A, Gold L. Chemistry and Biology; 4(11):833-843.
Date published: November 1, 1997Featured in this article: Donald Burke-Agüero.
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RNA aptamers to the adenosine moiety of S-adenosyl methionine: Structural inferences from variations on a theme and the reproducibility of SELEX. Burke DH, Gold L. Nucleic Acids Research; 25(0):2020-2024.
Date published: May 1, 1997Featured in this article: Donald Burke-Agüero.
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1996
Bent pseudoknots and novel RNA inhibitors of type 1 human immunodeficiency virus (HIV-1) reverse transcriptase. Burke DH, Scates L, Andrews K, Gold L. Journal of Molecular Biology; 264(4):650-666.
Date published: December 13, 1996Featured in this article: Donald Burke-Agüero.
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1994
Functional assignment of Erwinia herbicola Eho10 carotenoid genes expressed in Escherichia coli. Hundle B, Alberti M, Nievelstein V, Beyer P, Kleinig H, Armstrong GA, Burke DH, Hearst JE. MGG Molecular & General Genetics; 245(4):406-416.
Date published: July 1, 1994Featured in this article: Donald Burke-Agüero.
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1993
Circularly permuted tRNAs as specific photoaffinity probes of ribonuclease P RNA structure. Nolan JM, Burke DH, Pace NR. Science; 261(5122):762-765.
Date published: August 6, 1993Featured in this article: Donald Burke-Agüero.
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Early evolution of photosynthesis: Clues from nitrogenase and chlorophyll iron proteins. Burke DH, Hearst JE, Sidow A. Proceedings of the National Academy of Sciences of the United States of America; 90(15):7134-7138.
Date published: August 1, 1993Featured in this article: Donald Burke-Agüero.
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Regulation of carotenoid and bacteriochlorophyll biosynthesis genes and identification of an evolutionarily conserved gene required for bacteriochlorophyll accumulation. Armstrong GA, Cook DN, Ma D, Alberti M, Burke DH, Hearst JE. Journal of General Microbiology; 139(5):879-906.
Date published: May 1, 1993Featured in this article: Donald Burke-Agüero.
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The Rhodobacter capsulatus chlorin reductase-encoding locus, bchA, consists of three genes, bchX, bchY, and bchZ. Burke DH, Alberti M, Hearst JE. Journal of Bacteriology; 175(8):2407-2413.
Date published: April 1, 1993Featured in this article: Donald Burke-Agüero.
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bchFNBH Bacteriochlorophyll synthesis genes of Rhodobacter capsulatus and identification of the third subunit of light-independent protochlorophyllide reductase in bacteria and plants. Burke DH, Alberti M, Hearst JE. Journal of Bacteriology; 175(8):2414-2422.
Date published: April 1, 1993Featured in this article: Donald Burke-Agüero.
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The chlL (frxC) gene: Phylogenetic distribution in vascular plants and DNA sequence from Polystichum acrostichoides (Pteridophyta) and Synechococcus sp. 7002 (Cyanobacteria). Burke DH, Raubeson LA, Alberti M, Hearst JE, Jordan ET, Kirch SA, Valinski AEC, Conant DS, Stein DB. Plant Systematics and Evolution; 187(1-4):89-102.
Date published: March 1, 1993Featured in this article: Donald Burke-Agüero.
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1990
An RNA holliday junction? Structural and dynamic considerations of the bacteriophage T4 gene 60 interruption. Burke-Agüero DH, Hearst JE. Journal of Molecular Biology; 213(2):199-201.
Date published: May 20, 1990Featured in this article: Donald Burke-Agüero.
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