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Michael J. Petris

Michael J. Petris

Professor of Biochemistry

Phone: 573-882-9685
540d Life Sciences Center

The Petris lab investigates how minerals are accumulated within the body at the right locations and in the right concentrations. Certain conditions such as Alzheimer’s disease, cancer and microbial infection disrupt the cellular balance of minerals that may exacerbate the pathology or improve outcome. The Petris lab is focused on copper. This essential mineral is critical for many metabolic processes, including consumption of oxygen to generate of ATP, the energy source of the cell. However, it is potentially toxic if pathways that regulate its handling are dysfunctional. Using cells and animal models, the Petris lab is interested in how copper functions in Alzheimer’s disease, tumor growth, and microbial killing by the immune system.

News about Michael J. Petris

P2Y2 nucleotide receptors mediate metalloprotease-dependent phosphorylation of epidermal growth factor receptor and ErbB3 in human salivary gland cells. Ratchford AM, Baker OJ, Camden JM, Rikka S, Petris MJ, Seye CI, Erb L, Weisman GA. Journal of Biological Chemistry; 285(10):7545-7555.

Featured in this article: Olga Baker, Jean Camden, Michael Petris, Cheikh Seye, Gary Weisman.

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Rat parotid gland cell differentiation in three-dimensional culture. Baker OJ, Schulz DJ, Camden JM, Liao Z, Peterson TS, Seye CI, Petris MJ, Weisman GA. Tissue Engineering - Part C: Methods; 16(5):1135-1144.

Featured in this article: Olga Baker, Jean Camden, Cheikh Seye, Michael Petris, Gary Weisman.

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Trimers Conjugated to Fibrin Hydrogels Promote Salivary Gland Function. Dos Santos HT, Nam K, Brown CT, Dean SM, Lewis S, Pfeifer CS, Lei P, Petris MJ, Andreadis ST, Baker OJ. Journal of Dental Research; 100(3):268-275.

Featured in this article: Harim Tavares dos Santos, Kihoon Nam, Michael Petris, Olga Baker.

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